TOKYO, July 3 (AP) - (Kyodo)—(EDS: ADD INFO)
The health ministry said Thursday it has detected a genetic mutation of the new H1N1 strain of influenza A that develops resistance to Tamiflu, marking the first case of the new influenza in Japan that did not respond to the anti-flu drug.
The Health, Labor and Welfare Ministry said the Tamiflu-resistant virus was detected in a woman in her 40s infected with the new influenza in Osaka Prefecture.
The first case of HINI that showed resistance to Tamiflu was reported in Denmark at the end of last month.
The patient in Osaka is already recovering after being administered Relenza, another anti-flu drug.
According to the ministry, the female patient had been administered Tamiflu since May 18 as a preventive measure after she was found to have had close contact with another confirmed infected patient the previous day.
She developed a slight fever on May 24 and was confirmed infected with the new influenza on May 28. An analysis of a virus taken from her detected the genetic mutation that does not respond to Tamiflu on June 18.
There is no sign of any further spread of the Tamiflu-resistant virus as no other cases of the HINI influenza were reported around the patient, the ministry added.
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